Brimstone Flames

Brimstone Flames is a debuff inflicted by many sources throughout the Calamity Mod. If inflicted on an enemy, they lose 20 health per second. If inflicted on the player, they instead lose 8 health per second. The inflicted target will always emit bright red particles.

If the target is inflicted with Oiled, they lose 25 health per second instead of 20.

The player can become immune to Brimstone Flames by equipping the Asgardian Aegis accessory or consuming Purified Jam. Equipping the Abaddon or Asgard's Valor accessories will reduce the damage from Brimstone Flames.

From player
In addition to the causes listed below, items that inflict Elemental Mix will inflict Brimstone Flames as a part of that.