Calamity Mod Wiki
Type Debuff
Effects No health regeneration
-10 health per second, -4 defense, -15% move speed, and darkness debuff is inflicted. (if player)
-50 health per second and -4 defense. (if enemy)
Tooltip Rotting from the inside
If you were looking for something other than the Plague debuff, see Plague (disambiguation).

Plague is a debuff inflicted primarily by "plagued" enemies in the Jungle as well as weapons dropped by The Plaguebringer Goliath. It causes the target to lose 50 health per second and 4 defence as well as emitting large, green particles. When inflicted on a player, the player loses 10 health per second, 4 defense, and 15% movement speed. Additionally, vision is reduced similarly to the Darkness debuff, and the player emits large, green particles.

When the player has Alchemical Flask, Plaguebringer Carapace, Plague Hive, or Plague Reaper Vest equipped, they lose 5 health per second instead. Additionally, the Alchemical Flask and Plague Hive cancel out the vision loss effect too.


From player[]

In addition to the causes listed below, items that inflict Elemental Mix will inflict Plague as a part of that.

From Duration Chance
Acid Round Acid Round 3 seconds 100%
Alchemical Flask Alchemical Flask 2, 4, or 6 seconds (On attack)
3 seconds (Plague seekers)
Alpha Virus Alpha Virus 2 seconds (plague cell)
3 seconds (plague seeker)
Blight Spewer Blight Spewer 4 seconds 100%
Charged Dart Blaster Charged Dart Blaster 4 seconds (Explosion) 100%
Contagion Contagion 4 seconds (Arrow)
2 seconds (Orb)
Diseased Pike Diseased Pike 5 seconds (Spear)
3 seconds (Seeker)
Elemental Eruption Elemental Eruption 2 seconds 100%
Epidemic Shredder Epidemic Shredder 4 seconds (Boomerang)
3 seconds (Plague seekers)
Fuel Cell Bundle Fuel Cell Bundle 3 seconds 100%
Infected Remote Infected Remote 3 seconds (Contact)
2 seconds (Missile, Mini-Plaguebringer)
1 second (Plague Bee)
Malevolence Malevolence 10 seconds 100%
Pandemic Pandemic 4 seconds (Yoyo)
3 seconds (Seeker)
Pestilent Defiler Pestilent Defiler 6 seconds (Main shot)
3 seconds (Split shots)
Plague Hive Plague Hive 2, 4, or 6 seconds (On attack)
5 seconds (Bee/wasp projectiles)
3 seconds (Plague Seekers)
Plague Keeper Plague Keeper 5 seconds (Contact)
3 seconds (Dust)
Plague Reaper armor Plague Reaper armor 2 seconds (Plague Cinders) 100%
Plague Staff Plague Staff 5 seconds 100%
Plaguebringer armor Plaguebringer armor 5 seconds (Bees, Wasps, Dash)
2 seconds (On minion hits)
Plagued Fuel Pack Plagued Fuel Pack 4 seconds (Cloud) 100%
Plaguenade Plaguenade 3 seconds (Plague bees)
4 seconds (Plaguenade)
Soul Harvester Soul Harvester 4 seconds (Contact)
3 seconds (Soul Scythe)
Tactical Plague Engine Tactical Plague Engine 3 seconds (Missile) 100%
The Hive The Hive 3 seconds (RPG, Bomb, Rocket) 100%
The Syringe The Syringe 4 seconds (Syringe)
2 seconds (Glass and Cinders)
3 seconds (Bees)
Toxic Heart Toxic Heart 2 seconds (Aura) 100%
Virulence Virulence 4 seconds 100%
Wither Blossoms Staff Wither Blossoms Staff 3 seconds 100%

From NPCs[]

From Duration Chance
The Plaguebringer Goliath The Plaguebringer Goliath 4 seconds (Contact)
4 seconds (Plague Stinger explosions)
3 seconds (Plague Missiles)
Plague Homing Missile Plague Homing Missile 3 seconds 100%
Plague Charger Plague Charger 2 seconds 100%
Plaguebringer Plaguebringer 2 seconds (Contact)
5 seconds (Plague rocket)
4 seconds (Stinger explosion)
Viruling Viruling 3 seconds 100%
Pestilent Slime Pestilent Slime 3 seconds 100%
Melter Melter 3 seconds 100%
Plagueshell Plagueshell 3 seconds 100%

Immune NPCs[]

  • Trivia[]